Variation Browser
DownloadReceptor | Position | GPCRdb | Segment | Variant | Mutation type | Allele Frequency | Allele Count | Allele Number | Homozygotes | SIFT score | PolyPhen score | Functional annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Receptor | Position | GPCRdb | Segment | Variant | Mutation Type | Allele Frequency | Allele Count | Allele Number | Homozygotes | SIFT score | PolyPhen score | Functional annotation |
grm5_human | 1181 | C-term | N => GlnfsTer18 | frameshift | 9.102e-06 | 1 | 109864 | 0 | None | None | ||
grm5_human | 1169 | C-term | F => SerfsTer34 | frameshift | 1.222e-05 | 1 | 81834 | 0 | None | None | ||
grm5_human | 1149 | C-term | E => Ter | stop gained | 0.0003102 | 2 | 6448 | 0 | None | None | ||
grm5_human | 533 | N-term | T => AspfsTer6 | frameshift | 8.24e-06 | 1 | 121358 | 0 | None | None | ||
grm5_human | 469 | N-term | M => GlufsTer11 | frameshift | 1.157e-05 | 1 | 86458 | 0 | None | None | ||
grm5_human | 366 | N-term | R => Ter | stop gained | 8.271e-06 | 1 | 120902 | 0 | None | None | ||
grm5_human | 268 | N-term | L => Ter | stop gained | 3.68e-05 | 1 | 27174 | 0 | None | None | ||
grm5_human | 67 | N-term | Q => HisfsTer4 | frameshift | 4.244e-05 | 1 | 23562 | 0 | None | None | ||
grm5_human | 1207 | C-term | Q => E | missense | 8.639e-06 | 1 | 115754 | 0 | nan | 0.895 | ||
grm5_human | 1206 | C-term | T => S | missense | 8.631e-06 | 1 | 115866 | 0 | nan | 0.007 | ||
grm5_human | 1200 | C-term | L => P | missense | 0.0006885 | 80 | 116192 | 0 | nan | 0.984 | ||
grm5_human | 1193 | C-term | S => L | missense | 8.623e-06 | 1 | 115974 | 0 | nan | 0.558 | ||
grm5_human | 1190 | C-term | C => Y | missense | 1.729e-05 | 2 | 115644 | 0 | nan | 0.958 | ||
grm5_human | 1188 | C-term | A => T | missense | 8.696e-06 | 1 | 114998 | 0 | nan | 0.697 | ||
grm5_human | 1184 | C-term | V => E | missense | 8.832e-06 | 1 | 113220 | 0 | nan | 0.312 | ||
grm5_human | 1180 | C-term | P => L | missense | 9.136e-06 | 1 | 109462 | 0 | nan | 0.932 | ||
grm5_human | 1174 | C-term | D => A | missense | 4.2e-05 | 4 | 95236 | 0 | 1.0 | 0.004 | ||
grm5_human | 1173 | C-term | V => A | missense | 1.069e-05 | 1 | 93576 | 0 | nan | 0.047 | ||
grm5_human | 1161 | C-term | V => L | missense | 1.912e-05 | 1 | 52310 | 0 | 1.0 | 0.005 | ||
grm5_human | 1159 | C-term | E => D | missense | 3.97e-05 | 2 | 50374 | 0 | 1.0 | 0.034 | ||
grm5_human | 1149 | C-term | E => V | missense | 0.0002177 | 2 | 9186 | 0 | nan | 0.058 | ||
grm5_human | 1148 | C-term | P => T | missense | 0.000159 | 1 | 6290 | 0 | nan | 0.009 | ||
grm5_human | 1146 | C-term | A => S | missense | 0.0003973 | 2 | 5034 | 0 | nan | 0.022 | ||
grm5_human | 1141 | C-term | R => Q | missense | 0.0001259 | 1 | 7940 | 0 | nan | 0.016 | ||
grm5_human | 1140 | C-term | A => T | missense | 0.0001073 | 1 | 9318 | 0 | nan | 0.025 | ||
grm5_human | 1139 | C-term | A => V | missense | 9.917e-05 | 1 | 10084 | 0 | nan | 0.054 | ||
grm5_human | 1136 | C-term | A => S | missense | 7.233e-05 | 1 | 13826 | 0 | nan | 0.003 | ||
grm5_human | 1134 | C-term | Q => R | missense | 6.316e-05 | 1 | 15834 | 0 | nan | 0.0 | ||
grm5_human | 1130 | C-term | A => V | missense | 9.91e-05 | 2 | 20182 | 0 | nan | 0.012 | ||
grm5_human | 1130 | C-term | A => T | missense | 4.857e-05 | 1 | 20588 | 0 | nan | 0.008 | ||
grm5_human | 1127 | C-term | A => P | missense | 0.0001976 | 5 | 25302 | 0 | nan | 0.003 | ||
grm5_human | 1127 | C-term | A => T | missense | 7.905e-05 | 2 | 25302 | 0 | nan | 0.003 | ||
grm5_human | 1123 | C-term | V => I | missense | 1.645e-05 | 1 | 60794 | 0 | nan | 0.076 | ||
grm5_human | 1122 | C-term | E => K | missense | 3.304e-05 | 2 | 60534 | 0 | nan | 0.315 | ||
grm5_human | 1119 | C-term | P => S | missense | 3.318e-05 | 2 | 60286 | 0 | nan | 0.023 | ||
grm5_human | 1115 | C-term | I => V | missense | 1.634e-05 | 1 | 61206 | 0 | nan | 0.015 | ||
grm5_human | 1110 | C-term | T => A | missense | 1.628e-05 | 1 | 61416 | 0 | nan | 0.997 | ||
grm5_human | 1108 | C-term | T => A | missense | 1.635e-05 | 1 | 61180 | 0 | nan | 0.539 | ||
grm5_human | 1107 | C-term | T => K | missense | 4.932e-05 | 3 | 60826 | 0 | nan | 0.355 | ||
grm5_human | 1107 | C-term | T => A | missense | 4.929e-05 | 3 | 60860 | 0 | nan | 0.153 | ||
grm5_human | 1102 | C-term | E => Q | missense | 1.739e-05 | 1 | 57506 | 0 | nan | 0.549 | ||
grm5_human | 1099 | C-term | I => S | missense | 1.812e-05 | 1 | 55174 | 0 | nan | 0.007 | ||
grm5_human | 1096 | C-term | S => T | missense | 1.923e-05 | 1 | 52014 | 0 | nan | 0.01 | ||
grm5_human | 1091 | C-term | A => S | missense | 2.199e-05 | 1 | 45478 | 0 | nan | 0.061 | ||
grm5_human | 1088 | C-term | G => C | missense | 2.35e-05 | 1 | 42556 | 0 | nan | 0.378 | ||
grm5_human | 1086 | C-term | S => R | missense | 5.001e-05 | 2 | 39996 | 0 | nan | 0.116 | ||
grm5_human | 1085 | C-term | P => L | missense | 2.551e-05 | 1 | 39198 | 0 | nan | 0.052 | ||
grm5_human | 1085 | C-term | P => S | missense | 0.0001039 | 4 | 38506 | 0 | nan | 0.085 | ||
grm5_human | 1043 | C-term | H => P | missense | 0.0004139 | 6 | 14498 | 0 | nan | 0.058 | ||
grm5_human | 1040 | C-term | P => L | missense | 0.0005766 | 8 | 13874 | 0 | nan | 0.084 | ||
grm5_human | 1031 | C-term | S => W | missense | 8.498e-05 | 1 | 11768 | 0 | nan | 0.911 | ||
grm5_human | 1029 | C-term | A => V | missense | 8.64e-05 | 1 | 11574 | 0 | nan | 0.071 | ||
grm5_human | 1017 | C-term | R => H | missense | 9.42e-05 | 1 | 10616 | 0 | nan | 0.467 | ||
grm5_human | 1014 | C-term | A => E | missense | 9.438e-05 | 1 | 10596 | 0 | nan | 0.17 | ||
grm5_human | 1001 | C-term | Y => F | missense | 0.0003782 | 4 | 10576 | 0 | nan | 0.686 | PTM (Phosphorylation) | |
grm5_human | 980 | C-term | A => V | missense | 0.0001643 | 2 | 12170 | 0 | nan | 0.011 | ||
grm5_human | 980 | C-term | A => E | missense | 8.217e-05 | 1 | 12170 | 0 | nan | 0.321 | ||
grm5_human | 980 | C-term | A => T | missense | 7.744e-05 | 1 | 12914 | 0 | nan | 0.08 | ||
grm5_human | 978 | C-term | G => S | missense | 0.004681 | 81 | 17304 | 1 | nan | 0.118 | ||
grm5_human | 974 | C-term | V => L | missense | 2.47e-05 | 1 | 40484 | 0 | nan | 0.001 | ||
grm5_human | 973 | C-term | G => S | missense | 0.0003872 | 20 | 51648 | 0 | nan | 0.003 | ||
grm5_human | 969 | C-term | G => V | missense | 1.162e-05 | 1 | 86034 | 0 | nan | 0.0 | LB (polar (hydrogen bond), Van der Waals) | |
grm5_human | 969 | C-term | G => R | missense | 1.133e-05 | 1 | 88282 | 0 | nan | 0.001 | LB (polar (hydrogen bond), Van der Waals) | |
grm5_human | 967 | C-term | A => V | missense | 1.026e-05 | 1 | 97434 | 0 | nan | 0.021 | ||
grm5_human | 965 | C-term | A => S | missense | 6.731e-05 | 7 | 103990 | 0 | nan | 0.003 | ||
grm5_human | 963 | C-term | A => P | missense | 0.0001584 | 17 | 107290 | 0 | nan | 0.238 | ||
grm5_human | 962 | C-term | G => R | missense | 9.218e-06 | 1 | 108486 | 0 | nan | 0.3 | ||
grm5_human | 957 | C-term | E => Q | missense | 8.963e-06 | 1 | 111572 | 0 | 1.0 | 0.203 | ||
grm5_human | 954 | C-term | K => R | missense | 8.875e-06 | 1 | 112678 | 0 | nan | 0.996 | ||
grm5_human | 948 | C-term | V => I | missense | 8.785e-06 | 1 | 113826 | 0 | nan | 0.089 | LB (aromatic (face-to-edge)) | |
grm5_human | 946 | C-term | T => K | missense | 8.771e-06 | 1 | 114016 | 0 | nan | 0.999 | ||
grm5_human | 939 | C-term | K => R | missense | 8.73e-06 | 1 | 114548 | 0 | nan | 0.993 | ||
grm5_human | 939 | C-term | K => Q | missense | 8.73e-06 | 1 | 114550 | 0 | nan | 0.997 | ||
grm5_human | 938 | C-term | N => S | missense | 9.6e-05 | 11 | 114586 | 0 | nan | 0.167 | ||
grm5_human | 932 | C-term | R => H | missense | 8.72e-06 | 1 | 114674 | 0 | nan | 0.999 | ||
grm5_human | 930 | C-term | W => G | missense | 8.715e-06 | 1 | 114744 | 0 | nan | 0.997 | ||
grm5_human | 928 | C-term | H => Q | missense | 8.715e-06 | 1 | 114744 | 0 | nan | 0.572 | ||
grm5_human | 925 | C-term | R => Q | missense | 2.617e-05 | 3 | 114618 | 0 | nan | 0.228 | ||
grm5_human | 925 | C-term | R => G | missense | 8.726e-06 | 1 | 114606 | 0 | nan | 0.344 | ||
grm5_human | 924 | C-term | S => T | missense | 8.727e-06 | 1 | 114586 | 0 | 0.15 | 0.028 | ||
grm5_human | 922 | C-term | K => M | missense | 1.745e-05 | 2 | 114582 | 0 | nan | 0.751 | ||
grm5_human | 915 | C-term | V => I | missense | 1.756e-05 | 2 | 113902 | 0 | nan | 0.994 | ||
grm5_human | 911 | C-term | N => S | missense | 3.539e-05 | 4 | 113042 | 0 | nan | 0.994 | ||
grm5_human | 905 | C-term | A => E | missense | 8.4e-06 | 1 | 119054 | 0 | nan | 0.027 | ||
grm5_human | 905 | C-term | A => P | missense | 8.397e-06 | 1 | 119084 | 0 | nan | 0.135 | ||
grm5_human | 899 | C-term | M => V | missense | 4.184e-05 | 5 | 119492 | 0 | nan | 0.0 | ||
grm5_human | 895 | C-term | P => R | missense | 8.363e-06 | 1 | 119574 | 0 | nan | 0.697 | ||
grm5_human | 888 | C-term | S => L | missense | 7.535e-05 | 9 | 119436 | 0 | nan | 0.01 | PTM (Phosphorylation) | |
grm5_human | 884 | C-term | A => P | missense | 5.039e-05 | 6 | 119080 | 0 | 0.23 | 0.064 | ||
grm5_human | 883 | C-term | L => Q | missense | 8.403e-06 | 1 | 119000 | 0 | 0.01 | 0.047 | ||
grm5_human | 875 | C-term | T => N | missense | 8.872e-06 | 1 | 112716 | 0 | 0.48 | 0.02 | ||
grm5_human | 871 | C-term | S => F | missense | 0.000197 | 23 | 116766 | 0 | 0.02 | 0.998 | ||
grm5_human | 865 | C-term | L => V | missense | 8.326e-06 | 1 | 120104 | 0 | 0.03 | 0.996 | ||
grm5_human | 862 | C-term | L => I | missense | 3.317e-05 | 4 | 120584 | 0 | 0.18 | 0.487 | ||
grm5_human | 856 | C-term | A => G | missense | 8.261e-06 | 1 | 121046 | 0 | 0.12 | 0.345 | ||
grm5_human | 855 | C-term | A => T | missense | 4.129e-05 | 5 | 121092 | 0 | 0.29 | 0.691 | ||
grm5_human | 847 | C-term | V => I | missense | 1.649e-05 | 2 | 121266 | 0 | 0.21 | 0.99 | ||
grm5_human | 842 | C-term | V => M | missense | 5.771e-05 | 7 | 121298 | 0 | 0.01 | 0.999 | ||
grm5_human | 841 | C-term | T => N | missense | 8.244e-06 | 1 | 121306 | 0 | 0.2 | 0.997 | PTM (Phosphorylation (PRKCA)) | |
grm5_human | 836 | 8.53x53 | H8 | A => V | missense | 8.243e-06 | 1 | 121316 | 0 | 0.02 | 0.997 | |
grm5_human | 820 | 7.50x50 | TM7 | P => Q | missense | 8.242e-06 | 1 | 121330 | 0 | 0.01 | 1.0 | GP (contact) |
grm5_human | 820 | 7.50x50 | TM7 | P => L | missense | 8.242e-06 | 1 | 121330 | 0 | 0.0 | 1.0 | GP (contact) |
grm5_human | 815 | 7.45x46 | TM7 | G => A | missense | 8.243e-06 | 1 | 121320 | 0 | 1.0 | 0.519 | |
grm5_human | 814 | 7.44x45 | TM7 | L => P | missense | 8.243e-06 | 1 | 121320 | 0 | 0.0 | 1.0 | SodiumPocket MicroSwitch |
grm5_human | 775 | 6.40x40 | TM6 | A => T | missense | 8.238e-06 | 1 | 121394 | 0 | 0.0 | 0.96 | |
grm5_human | 769 | ICL3 | N => I | missense | 8.238e-06 | 1 | 121388 | 0 | 0.0 | 0.998 | ||
grm5_human | 766 | ICL3 | A => T | missense | 8.238e-06 | 1 | 121384 | 0 | 0.01 | 0.99 | ||
grm5_human | 761 | 5.61x61 | TM5 | T => S | missense | 8.239e-06 | 1 | 121380 | 0 | 0.02 | 0.978 | GP (contact) |
grm5_human | 736 | 5.36x36 | TM5 | T => S | missense | 8.239e-06 | 1 | 121374 | 0 | 1.0 | 0.771 | |
grm5_human | 734 | 45.51x51 | ECL2 | N => T | missense | 8.239e-06 | 1 | 121372 | 0 | 0.03 | 0.999 | |
grm5_human | 729 | ECL2 | V => A | missense | 8.238e-06 | 1 | 121382 | 0 | 0.0 | 0.997 | ||
grm5_human | 726 | ECL2 | I => V | missense | 8.239e-06 | 1 | 121378 | 0 | 0.16 | 0.994 | ||
grm5_human | 725 | ECL2 | S => N | missense | 8.239e-06 | 1 | 121372 | 0 | 0.02 | 0.998 | ||
grm5_human | 719 | ECL2 | I => T | missense | 8.24e-06 | 1 | 121366 | 0 | 0.2 | 0.257 | ||
grm5_human | 715 | 4.54x54 | TM4 | E => G | missense | 8.24e-06 | 1 | 121366 | 0 | 0.0 | 0.999 | |
grm5_human | 714 | 4.53x53 | TM4 | M => I | missense | 8.24e-06 | 1 | 121366 | 0 | 0.21 | 0.029 | |
grm5_human | 714 | 4.53x53 | TM4 | M => V | missense | 1.648e-05 | 2 | 121364 | 0 | 0.02 | 0.052 | |
grm5_human | 711 | 4.50x50 | TM4 | L => I | missense | 8.24e-06 | 1 | 121362 | 0 | 0.04 | 0.999 | |
grm5_human | 709 | 4.48x48 | TM4 | V => I | missense | 0.000445 | 54 | 121360 | 2 | 0.49 | 0.144 | |
grm5_human | 699 | 4.38x38 | TM4 | I => L | missense | 1.648e-05 | 2 | 121348 | 0 | 0.25 | 0.018 | |
grm5_human | 695 | 4.34x34 | TM4 | V => A | missense | 8.241e-06 | 1 | 121350 | 0 | 0.01 | 0.741 | |
grm5_human | 690 | 4.29x29 | TM4 | A => V | missense | 8.242e-06 | 1 | 121326 | 0 | 0.0 | 0.999 | |
grm5_human | 690 | 4.29x29 | TM4 | A => S | missense | 8.242e-06 | 1 | 121336 | 0 | 0.03 | 0.999 | |
grm5_human | 689 | 4.28x28 | TM4 | S => I | missense | 8.242e-06 | 1 | 121328 | 0 | 0.0 | 1.0 | |
grm5_human | 679 | ICL2 | K => E | missense | 8.247e-06 | 1 | 121258 | 0 | 0.0 | 0.998 | ||
grm5_human | 670 | 3.55x55 | TM3 | A => T | missense | 8.255e-06 | 1 | 121146 | 0 | 0.0 | 1.0 | |
grm5_human | 668 | 3.53x53 | TM3 | R => H | missense | 8.256e-06 | 1 | 121122 | 0 | 0.0 | 1.0 | SodiumPocket MicroSwitch |
grm5_human | 663 | 3.48x48 | TM3 | V => A | missense | 8.258e-06 | 1 | 121100 | 0 | 0.06 | 0.997 | |
grm5_human | 657 | 3.42x42 | TM3 | M => V | missense | 8.259e-06 | 1 | 121076 | 0 | 0.08 | 0.989 | |
grm5_human | 652 | 3.37x37 | TM3 | G => C | missense | 1.653e-05 | 2 | 121018 | 0 | 0.04 | 1.0 | |
grm5_human | 650 | 3.35x35 | TM3 | G => V | missense | 8.262e-06 | 1 | 121032 | 0 | 0.29 | 1.0 | |
grm5_human | 644 | 3.29x29 | TM3 | C => Y | missense | 8.259e-06 | 1 | 121082 | 0 | 0.0 | 1.0 | |
grm5_human | 638 | ECL1 | K => E | missense | 8.254e-06 | 1 | 121156 | 0 | 0.01 | 0.998 | ||
grm5_human | 637 | ECL1 | A => V | missense | 8.253e-06 | 1 | 121164 | 0 | 0.0 | 0.941 | ||
grm5_human | 635 | 2.56x56 | TM2 | L => F | missense | 8.25e-06 | 1 | 121216 | 0 | 0.0 | 1.0 | |
grm5_human | 630 | 2.51x51 | TM2 | L => F | missense | 8.247e-06 | 1 | 121256 | 0 | 0.06 | 1.0 | |
grm5_human | 628 | 2.49x49 | TM2 | G => S | missense | 8.245e-06 | 1 | 121288 | 0 | 0.19 | 1.0 | |
grm5_human | 620 | 2.41x41 | TM2 | I => L | missense | 8.244e-06 | 1 | 121298 | 0 | 0.06 | 0.994 | |
grm5_human | 620 | 2.41x41 | TM2 | I => F | missense | 8.244e-06 | 1 | 121298 | 0 | 0.0 | 0.999 | |
grm5_human | 616 | 2.37x37 | TM2 | E => K | missense | 8.245e-06 | 1 | 121290 | 0 | 0.0 | 1.0 | |
grm5_human | 605 | ICL1 | R => H | missense | 1.65e-05 | 2 | 121230 | 0 | 0.14 | 0.052 | ||
grm5_human | 605 | ICL1 | R => C | missense | 3.3e-05 | 4 | 121228 | 0 | 0.01 | 0.962 | ||
grm5_human | 603 | 1.63x63 | TM1 | I => M | missense | 8.25e-06 | 1 | 121208 | 0 | 0.28 | 0.016 | |
grm5_human | 591 | 1.51x51 | TM1 | L => F | missense | 8.272e-06 | 1 | 120886 | 0 | 0.08 | 0.986 | |
grm5_human | 590 | 1.50x50 | TM1 | G => D | missense | 8.273e-06 | 1 | 120874 | 0 | 0.0 | 1.0 | |
grm5_human | 585 | 1.45x45 | TM1 | V => A | missense | 8.3e-06 | 1 | 120480 | 0 | 0.22 | 0.221 | |
grm5_human | 582 | 1.42x42 | TM1 | A => S | missense | 8.349e-06 | 1 | 119776 | 0 | 0.0 | 0.996 | |
grm5_human | 571 | N-term | Q => R | missense | 1.783e-05 | 2 | 112192 | 0 | 0.44 | 0.08 | ||
grm5_human | 560 | N-term | D => G | missense | 8.255e-06 | 1 | 121132 | 0 | 0.19 | 0.05 | ||
grm5_human | 553 | N-term | Q => H | missense | 8.249e-06 | 1 | 121232 | 0 | 0.04 | 0.516 | ||
grm5_human | 552 | N-term | C => Y | missense | 8.248e-06 | 1 | 121248 | 0 | 0.0 | 1.0 | ||
grm5_human | 551 | N-term | A => S | missense | 8.246e-06 | 1 | 121270 | 0 | 0.05 | 0.999 | ||
grm5_human | 550 | N-term | K => N | missense | 8.246e-06 | 1 | 121266 | 0 | 0.01 | 0.524 | ||
grm5_human | 535 | N-term | T => I | missense | 8.24e-06 | 1 | 121352 | 0 | 0.03 | 0.999 | ||
grm5_human | 529 | N-term | S => G | missense | 8.241e-06 | 1 | 121346 | 0 | 0.0 | 0.924 | ||
grm5_human | 513 | N-term | E => D | missense | 8.358e-06 | 1 | 119650 | 0 | 0.14 | 0.084 | ||
grm5_human | 506 | N-term | I => N | missense | 8.273e-06 | 1 | 120882 | 0 | 0.06 | 0.534 | ||
grm5_human | 504 | N-term | S => R | missense | 8.268e-06 | 1 | 120946 | 0 | 0.04 | 0.101 | ||
grm5_human | 504 | N-term | S => N | missense | 8.268e-06 | 1 | 120950 | 0 | 0.14 | 0.015 | ||
grm5_human | 498 | N-term | E => Q | missense | 8.27e-06 | 1 | 120924 | 0 | 0.24 | 0.997 | ||
grm5_human | 497 | N-term | D => A | missense | 8.269e-06 | 1 | 120936 | 0 | 0.47 | 0.171 | ||
grm5_human | 497 | N-term | D => V | missense | 8.269e-06 | 1 | 120936 | 0 | 0.18 | 0.432 | ||
grm5_human | 495 | N-term | D => N | missense | 8.274e-06 | 1 | 120856 | 0 | 0.24 | 0.005 | ||
grm5_human | 492 | N-term | L => I | missense | 8.29e-06 | 1 | 120622 | 0 | 0.02 | 0.999 | ||
grm5_human | 482 | N-term | I => V | missense | 8.668e-06 | 1 | 115366 | 0 | 1.0 | 0.015 | ||
grm5_human | 478 | N-term | Y => F | missense | 3.641e-05 | 4 | 109858 | 0 | 0.08 | 0.438 | ||
grm5_human | 476 | N-term | K => E | missense | 9.68e-06 | 1 | 103306 | 0 | 0.82 | 0.017 | ||
grm5_human | 475 | N-term | G => R | missense | 9.892e-06 | 1 | 101096 | 0 | 0.07 | 0.964 | ||
grm5_human | 474 | N-term | M => T | missense | 2.031e-05 | 2 | 98454 | 0 | 0.61 | 0.012 | ||
grm5_human | 473 | N-term | E => Q | missense | 2.095e-05 | 2 | 95486 | 0 | 0.63 | 0.004 | ||
grm5_human | 458 | N-term | E => Q | missense | 8.324e-06 | 1 | 120134 | 0 | 0.24 | 0.113 | ||
grm5_human | 453 | N-term | T => M | missense | 0.00726 | 874 | 120390 | 28 | 0.2 | 0.051 | ||
grm5_human | 453 | N-term | T => R | missense | 8.306e-06 | 1 | 120390 | 0 | 0.45 | 0.389 | ||
grm5_human | 437 | N-term | L => R | missense | 8.258e-06 | 1 | 121096 | 0 | 0.0 | 1.0 | ||
grm5_human | 437 | N-term | L => V | missense | 8.257e-06 | 1 | 121108 | 0 | 0.0 | 0.999 | ||
grm5_human | 435 | N-term | R => Q | missense | 2.477e-05 | 3 | 121122 | 0 | 0.08 | 0.016 | ||
grm5_human | 435 | N-term | R => L | missense | 8.256e-06 | 1 | 121122 | 0 | 0.01 | 0.12 | ||
grm5_human | 435 | N-term | R => W | missense | 2.477e-05 | 3 | 121134 | 0 | 0.0 | 0.881 | ||
grm5_human | 432 | N-term | I => T | missense | 8.252e-06 | 1 | 121188 | 0 | 0.0 | 0.948 | ||
grm5_human | 416 | N-term | M => I | missense | 1.649e-05 | 2 | 121268 | 0 | 0.06 | 0.048 | ||
grm5_human | 414 | N-term | M => V | missense | 8.245e-06 | 1 | 121280 | 0 | 0.0 | 0.99 | ||
grm5_human | 383 | N-term | S => G | missense | 2.499e-05 | 3 | 120050 | 0 | 1.0 | 0.396 | ||
grm5_human | 375 | N-term | S => N | missense | 4.143e-05 | 5 | 120700 | 0 | 0.41 | 0.009 | ||
grm5_human | 375 | N-term | S => G | missense | 8.283e-06 | 1 | 120730 | 0 | 0.39 | 0.122 | ||
grm5_human | 370 | N-term | F => S | missense | 8.276e-06 | 1 | 120828 | 0 | 0.17 | 0.011 | ||
grm5_human | 369 | N-term | G => V | missense | 2.482e-05 | 3 | 120862 | 0 | 0.09 | 1.0 | ||
grm5_human | 366 | N-term | R => Q | missense | 2.482e-05 | 3 | 120894 | 0 | 0.2 | 0.08 | ||
grm5_human | 364 | N-term | Q => R | missense | 8.27e-06 | 1 | 120924 | 0 | 0.0 | 0.472 | ||
grm5_human | 350 | N-term | H => N | missense | 8.265e-06 | 1 | 120986 | 0 | 0.13 | 0.143 | ||
grm5_human | 347 | N-term | E => K | missense | 8.266e-06 | 1 | 120978 | 0 | 0.07 | 0.676 | ||
grm5_human | 345 | N-term | R => Q | missense | 1.653e-05 | 2 | 120994 | 0 | 0.09 | 0.008 | ||
grm5_human | 333 | N-term | D => N | missense | 2.479e-05 | 3 | 121010 | 0 | 0.27 | 0.713 | ||
grm5_human | 332 | N-term | P => S | missense | 2.479e-05 | 3 | 121010 | 0 | 0.04 | 0.29 | ||
grm5_human | 322 | N-term | V => L | missense | 8.269e-06 | 1 | 120940 | 0 | 0.29 | 0.257 | ||
grm5_human | 315 | N-term | D => Y | missense | 8.277e-06 | 1 | 120822 | 0 | 0.0 | 0.959 | ||
grm5_human | 304 | N-term | S => I | missense | 8.3e-06 | 1 | 120478 | 0 | 0.0 | 0.997 | ||
grm5_human | 298 | N-term | E => D | missense | 0.0001489 | 18 | 120856 | 0 | 0.02 | 0.292 | ||
grm5_human | 296 | N-term | A => E | missense | 8.263e-06 | 1 | 121022 | 0 | 0.21 | 0.373 | ||
grm5_human | 295 | N-term | L => V | missense | 3.303e-05 | 4 | 121088 | 0 | 1.0 | 0.566 | ||
grm5_human | 294 | N-term | G => R | missense | 3.303e-05 | 4 | 121110 | 0 | 0.37 | 0.028 | ||
grm5_human | 292 | N-term | R => C | missense | 8.252e-06 | 1 | 121182 | 0 | 0.0 | 1.0 | ||
grm5_human | 290 | N-term | M => V | missense | 8.248e-06 | 1 | 121240 | 0 | 0.05 | 0.909 | ||
grm5_human | 282 | N-term | T => M | missense | 8.245e-06 | 1 | 121288 | 0 | 0.0 | 1.0 | PTM (Phosphorylation) | |
grm5_human | 281 | N-term | M => T | missense | 8.243e-06 | 1 | 121314 | 0 | 0.02 | 0.987 | ||
grm5_human | 271 | N-term | A => V | missense | 8.253e-06 | 1 | 121174 | 0 | 0.03 | 0.885 | ||
grm5_human | 263 | N-term | K => R | missense | 4.16e-05 | 5 | 120190 | 0 | 0.24 | 0.007 | ||
grm5_human | 213 | N-term | Y => F | missense | 8.399e-06 | 1 | 119058 | 0 | 0.01 | 0.828 | ||
grm5_human | 210 | N-term | N => S | missense | 8.344e-06 | 1 | 119852 | 0 | 0.02 | 0.493 | ||
grm5_human | 197 | N-term | Q => K | missense | 8.244e-06 | 1 | 121302 | 0 | 0.02 | 0.994 | ||
grm5_human | 189 | N-term | M => V | missense | 8.241e-06 | 1 | 121344 | 0 | 0.02 | 0.989 | ||
grm5_human | 167 | N-term | I => V | missense | 8.242e-06 | 1 | 121336 | 0 | 0.0 | 0.992 | ||
grm5_human | 147 | N-term | I => V | missense | 8.241e-06 | 1 | 121350 | 0 | 0.16 | 0.985 | ||
grm5_human | 146 | N-term | V => I | missense | 8.24e-06 | 1 | 121352 | 0 | 0.05 | 0.546 | ||
grm5_human | 144 | N-term | V => A | missense | 8.241e-06 | 1 | 121348 | 0 | 0.5 | 0.997 | ||
grm5_human | 138 | N-term | R => H | missense | 1.648e-05 | 2 | 121356 | 0 | 0.06 | 0.055 | ||
grm5_human | 138 | N-term | R => C | missense | 8.24e-06 | 1 | 121352 | 0 | 0.02 | 0.863 | ||
grm5_human | 137 | N-term | F => L | missense | 8.24e-06 | 1 | 121358 | 0 | 0.68 | 0.002 | ||
grm5_human | 136 | N-term | S => P | missense | 8.24e-06 | 1 | 121356 | 0 | 0.38 | 0.01 | ||
grm5_human | 130 | N-term | V => M | missense | 2.472e-05 | 3 | 121358 | 0 | 0.12 | 0.767 | ||
grm5_human | 128 | N-term | R => H | missense | 2.472e-05 | 3 | 121360 | 0 | 0.09 | 0.937 | ||
grm5_human | 125 | N-term | G => V | missense | 8.241e-06 | 1 | 121346 | 0 | 0.01 | 0.678 | ||
grm5_human | 122 | N-term | E => G | missense | 8.241e-06 | 1 | 121338 | 0 | 0.05 | 0.083 | ||
grm5_human | 121 | N-term | E => D | missense | 8.242e-06 | 1 | 121330 | 0 | 1.0 | 0.046 | ||
grm5_human | 121 | N-term | E => K | missense | 8.242e-06 | 1 | 121324 | 0 | 0.05 | 0.699 | ||
grm5_human | 119 | N-term | S => F | missense | 1.649e-05 | 2 | 121318 | 0 | 0.0 | 0.974 | ||
grm5_human | 115 | N-term | D => E | missense | 0.0001319 | 16 | 121300 | 0 | 0.03 | 0.994 | ||
grm5_human | 98 | N-term | S => Y | missense | 8.255e-06 | 1 | 121146 | 0 | 0.0 | 1.0 | PTM (Phosphorylation) | |
grm5_human | 87 | N-term | P => L | missense | 8.273e-06 | 1 | 120878 | 0 | 0.0 | 1.0 | ||
grm5_human | 80 | N-term | N => S | missense | 8.284e-06 | 1 | 120716 | 0 | 0.0 | 0.999 | ||
grm5_human | 76 | N-term | L => V | missense | 8.292e-06 | 1 | 120604 | 0 | 0.16 | 0.997 | ||
grm5_human | 65 | N-term | G => D | missense | 8.267e-06 | 1 | 120964 | 0 | 0.0 | 1.0 | ||
grm5_human | 61 | N-term | R => H | missense | 8.261e-06 | 1 | 121050 | 0 | 0.01 | 0.997 | ||
grm5_human | 59 | N-term | A => V | missense | 8.256e-06 | 1 | 121120 | 0 | 0.02 | 0.347 | ||
grm5_human | 45 | N-term | H => Q | missense | 8.249e-06 | 1 | 121222 | 0 | 0.06 | 0.981 | ||
grm5_human | 35 | N-term | I => M | missense | 2.476e-05 | 3 | 121182 | 0 | 0.01 | 0.828 | ||
grm5_human | 31 | N-term | M => V | missense | 8.254e-06 | 1 | 121160 | 0 | 0.04 | 0.046 | ||
grm5_human | 28 | N-term | V => M | missense | 8.255e-06 | 1 | 121142 | 0 | 0.0 | 0.843 | ||
grm5_human | 27 | N-term | V => M | missense | 8.255e-06 | 1 | 121146 | 0 | 0.05 | 0.999 | ||
grm5_human | 19 | N-term | S => G | missense | 8.271e-06 | 1 | 120898 | 0 | 0.23 | 0.138 | ||
grm5_human | 17 | N-term | R => H | missense | 2.484e-05 | 3 | 120790 | 0 | 0.05 | 0.389 | ||
grm5_human | 14 | N-term | E => G | missense | 3.316e-05 | 4 | 120640 | 0 | 0.24 | 0.0 | ||
grm5_human | 9 | N-term | V => I | missense | 8.331e-06 | 1 | 120040 | 0 | 0.16 | 0.001 | ||
grm5_human | 2 | N-term | V => A | missense | 6.768e-05 | 8 | 118198 | 0 | nan | 0.0 |
Residue
- deleterious missense variants are shown in red
- tolerated missense variants are shown in green
- loss of function mutations ('stop gained' or 'frameshift' in the coding region) are shown in blue